Human Lung Epithelial Cell Line

A549 cells are adenocarcinomic human alveolar basal epithelial cells and constitute a cell line that was first developed in 1972 by d.

Human lung epithelial cell line.

Against human lung cancer crl 9482 bbm lung bronchus carcinogen homo sapiens. Type i cells are large squamous cells whose thin cytoplasmic extensions cover 95 of the internal surface area. Some researcher use human normal lung fibroblasts hel 299 and mrc 5 cells while others use normal cell lines that don t belong to lung tissue. Lung cancer and normal cell lines.

Respiratory epithelium or airway epithelium is a type of ciliated columnar epithelium found lining most of the respiratory tract as respiratory mucosa where it serves to moisten and protect the airways. I want to use only normal lung cell not from other. It is not present in the vocal cords of the larynx or the oropharynx and laryngopharynx where instead the epithelium is stratified squamous. Bronchial tracheal epithelial cells atcc offers an assortment of products for the culture of airway epithelial cells.

The cell lines used in this study are the beas 2b a human bronchial epithelial cell line wi 38 a diploid fibroblast cell line of human fetal lung tissue origin a549 and nci h1703 two human non small cell lung carcinoma nsclc cell lines all of which were collected in our laboratory. Retains ion transport and other properties that are comparable to the native cells. Technical resources pulmonary alveolar epithelial cells paepic comprised of alveolar type i and type ii epithelial cells line more than 99 of the internal surface area of the lung. Human bronchial epithelial cell line hbe1 immortalized human bronchial epithelial cell line hbe1 derived from a non cf individual.

The cells have been derived from the surface epithelium of normal human bronchial tracheal tissue or from the surface epithelium of normal human bronchioles. Small cell lung cancer homo sapiens 59 years caucasian the cells do not express vasopressin oxytocin or gastrin releasing peptide. Lung epithelial cells the investigation of the human lung and its diseases is an important issue for drug development processes although it is hampered by the availability of suitable in vitro models.